NEET 2018, Biology Q87: Muscle
NEET2018Paper 2018Biology
Q.
. Calcium is important in skeletal muscle contraction because it
- A
Binds to troponin to remove the masking of active sites on actin for myosin.
- B
Detaches the myosin head from the actin filament.
- C
Activates the myosin ATPase by binding to it.
- D
Prevents the formation of bonds between the myosin cross bridges and the actin filament.
Solution
Signal for contraction increase Ca++ level many folds in the sarcoplasm.
Ca++ now binds with sub-unit of troponin (troponin "C") which is masking the active site on actin filament and displaces the sub-unit of troponin.
Once the active site is exposed, head of the myosin attaches and initiate contraction by sliding the actin over myosin.
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