JEE Advanced2024Paper 1CHEM-I
Q.
Aspartame, an artificial sweetener, is a dipeptide aspartyl phenylalanine methyl ester. The structure of aspartame is

- A

- B

- C

- D

Solution
Aspartame is L--aspartyl-L-phenylalanine methyl ester. The dipeptide is formed by an amide bond between the -carboxyl group of aspartic acid and the -amino group of phenylalanine. The C-terminal carboxyl group (on the phenylalanine side) is then methylated to give the methyl ester.
Key structural features that identify the correct option:
1. Free -amino group on the aspartate end.
2. The free -carboxyl (side-chain -CH-COOH) remains on aspartate.
3. Amide (peptide) bond connecting aspartate's -COOH to phenylalanine's -NH.
4. Methyl ester (-COOMe) on phenylalanine's -carbon.
Option (B) matches all four features.