Fundamentholfundamenthol
NEET2023Biology
Q.

Melonate inhibits the growth of pathogenic bacteria by inhibiting the activity of:

  1. A

    Succinic dehydrogenase

  2. B

    Amylase

  3. C

    Lipase

  4. D

    Dinitrogenase

Solution

Malonate (the conventional spelling) is the classic competitive inhibitor of succinate dehydrogenase: its structure closely resembles succinate, so it binds the active site without being oxidised. This blocks the TCA cycle and starves the bacterial cell of energy.

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