NEET 2023, Biology Q37: Enzymes
NEET2023Biology
Q.
Melonate inhibits the growth of pathogenic bacteria by inhibiting the activity of:
- A
Succinic dehydrogenase
- B
Amylase
- C
Lipase
- D
Dinitrogenase
Solution
Malonate (the conventional spelling) is the classic competitive inhibitor of succinate dehydrogenase: its structure closely resembles succinate, so it binds the active site without being oxidised. This blocks the TCA cycle and starves the bacterial cell of energy.
Concept behind this question
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