Fundamentholfundamenthol
NEET2024Biology
Q.

Inhibition of Succinic dehydrogenase enzyme by malonate is a classical example of:

  1. A

    Competitive inhibition

  2. B

    Enzyme activation

  3. C

    Cofactor inhibition

  4. D

    Feedback inhibition

Solution

Malonate has a structure closely resembling that of succinate (the natural substrate of succinic dehydrogenase). It competes with succinate for the active site without being converted to product. This is the textbook example of competitive inhibition.

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