Fundamentholfundamenthol
NEET2024Biology
Q.

Which of the following statement is correct regarding the process of replication in E. coli?

  1. A

    The DNA dependent DNA polymerase catalyses polymerization in 5' 3' as well as 3' 5' direction

  2. B

    The DNA dependent DNA polymerase catalyses polymerization in 5' 3' direction

  3. C

    The DNA dependent DNA polymerase catalyses polymerization in one direction that is 3' 5'

  4. D

    The DNA dependent RNA polymerase catalyses polymerization in one direction, that is 5' 3'

Solution

DNA-dependent DNA polymerase can add new nucleotides only to the free 3'-OH end of the growing strand; therefore polymerisation proceeds strictly in the 5' 3' direction. (The RNA polymerase statement in option 4 is also 5' 3', but the question asks about replication, where DNA polymerase is the relevant enzyme.)

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