Fundamentholfundamenthol
NEET2026Biology
Q.

Which one of the following disorders is caused by the substitution of Glutamic acid (Glu) by Valine (Val) at the sixth position of the beta globin chain of the haemoglobin molecule?

  1. A

    Thalassemia

  2. B

    Sickle-cell anaemia

  3. C

    Phenylketonuria

  4. D

    Haemophilia

Solution

Sickle-cell anaemia is an autosomal recessive disorder caused by the substitution of glutamic acid (Glu) by valine (Val) at the sixth position of the beta globin chain of haemoglobin.

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